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posted by Sunnyshe
21 May 2023


Last reply: 1 month ago

I'm currently on letrozole for estrogen positive breast cancer. I have completed my surgery and radiotherapy treatment. I've been on letrozole for about 10 weeks now, I'm finding the side effects very difficult and they are impacting my daily life. I have joint and muscle discomfort, along with very low energy. My G.P has given me paracetamol to help off set the pain, and I am also on Vimovo. When I return for my follow-up oncology appointment, I will mention these side effects. My main question is, is there anything oncology can add to my treatment care to help with these symptoms, also will things improve over time, or would I be best to change to an alternative medication to letrozole?
Thank you in advance.



commented by Cancer Nurse
23 May 2023

4 months ago

Dear Sunnyshe

Thank you for posting on our online community. I am sorry to hear of the impact Letrozole is having on your daily life. These side effects do make it so hard to do the things you would like to do without discomfort. I am afraid it will be your oncologist who will discuss this with you and if an alternative treatment is possible or if a different brand of Letrozole would help. You might also ask you consultant if you could speak to a physio for their advice.

Meanwhile if you would like to phone our support line and speak to a cancer nurse about the various supports that might be helpful to you at this time and tips on managing fatigue-our number is 1800 200 700 & we are here Mon-Fri 9-5pm. We could also discuss the various exercise programmes that may be in your area that may be of help also.

You have been through a lot over the last few months. I do hope we will hear from you.

Kind regards

Cancer Nurse

commented by jarlethb
04 August 2023

1 month ago

hi there.
I have been on letrozole for over a year now and the first 6 months were pretty awful. pain so bad in my feet it felt like my bones were broken and put back badly. But a god send has been a supplement of Glucosamine and Chondroitin. But it takes 3 months on it before u notice a change for the better. I used to be like an old woman getting up from my chair but that has lessened. I also from the get go....after doing some research...demanded that my pharmacy provide me with the original Femara rather than a generic version as the original is said to have less side effects. I would also advise that u walk a bit if possible as that also helps with the stiffness and pain. I hope u are doing well. hugs. x. J

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