Thyroid cancer
Treatment
How is thyroid cancer treated?
Treatment for thyroid cancer includes surgery, radioactive iodine therapy and thyroid hormone therapy. The right treatment plan for you will depend mainly on the type of thyroid cancer you have and the stage of your cancer. Your doctor will recommend the best treatment for you.
Surgery for thyroid cancer
The aim of surgery is to remove the cancer and the area close to it. Surgery is the most common treatment for thyroid cancer. There are different ways of doing surgery for thyroid cancer. The best type for you will depend on the stage of your cancer.
A small cut is usually made in the centre of your neck to get directly at your gland. If any tissue is left behind after surgery, you might need radioiodine therapy later.
Your surgeon might need to remove some of the tissues in the area around the thyroid gland if you have anaplastic thyroid cancer or if the cancer has begun to spread outside the thyroid gland.
The thyroid gland has 2 halves called lobes. Sometimes it is possible to remove just the affected lobe. This is called a lobectomy or partial thyroidectomy.
Your surgeon might remove some or all of the lymph nodes close to your thyroid gland during your thyroid cancer surgery. These can be examined under a microscope to see if cancer has spread to them or not. Removing the lymph nodes is called a lymphadenectomy or a neck dissection. As many nodes as possible are removed to prevent the cancer from coming back.
Side-effects of thyroid surgery
With all surgeries there is a small risk of bleeding and infection.
It is also common to feel tired or weak for a few weeks after your surgery. The time it takes to heal is different for everyone.
You will have a small scar across the front of your neck just above your collar bone. The scar will look red or dark at first but will fade with time. It is usually very neat and hardly noticeable.
Other possible side-effects
Sometimes there may be slight damage to the nerves to the voicebox (larynx). This can make your voice sound hoarse and weak. In most cases it a temporary problem, but it can be permanent for a very small number of people.
If there is damage to your parathyroid glands during surgery, the calcium levels in your blood may drop. Signs of low calcium levels include tingling in your hands, feet or around your mouth. Or you may have unusual muscle movements, such as jerking or muscle cramps. You will have regular blood tests to check the calcium levels in your blood. If needed, your doctor will prescribe calcium, and possibly vitamin D, until your levels are normal again.
You may experience some neck stiffness for a few days or weeks after your surgery. Your doctor will prescribe painkillers to help with this.
It is natural to be worried about scars after surgery. You will have a small scar across the front of your neck just above your collar bone. The scar will look red or dark at first but will fade with time. It is usually very neat and fades to a pale silver, depending on your complexion.
Radioactive iodine therapy
This is a type of internal radiotherapy. It can destroy tiny amounts of normal thyroid tissue or cancer cells that may have been left behind after surgery.
You might also get this treatment if some of the tumour could not be removed during surgery or if your cancer recurred (came back).
You may have to wait several weeks to recover after surgery before having this treatment. You will be referred to a specialist centre for this treatment if you need it.
Not all patients need radioactive iodine therapy.
Thyroid hormone therapy
If your thyroid gland has been removed, you will need thyroid hormone therapy to replace the thyroid hormones that can no longer be made in your body.
Thyroid hormone therapy also reduces the amount of thyroid-stimulating hormone (TSH) in your body, which can stop any surviving thyroid cells from working and help to prevent the cancer coming back.
The usual thyroid hormone replacement is thyroxine, which is also called T4. You will be given this replacement for the rest of your life.
Without these hormones, you would develop signs and symptoms of an underactive thyroid. This is called hypothyroidism. Signs of it include weight gain, tiredness, dry skin and hair, and physical and mental slowness.
Most people only need to take the drug once a day, but at the same time every day. It may take some months to find the correct dosage for you. As a result, you will have blood tests to check your hormone levels regularly.
For many patients, an important part of treatment is keeping thyroid-stimulating hormone (TSH) levels low. TSH is made by the pituitary gland in your brain and it can encourage the growth of thyroid cancer cells.
By keeping TSH levels low, it prevents thyroid cancer developing. By giving higher than normal doses of thyroid hormone, TSH levels can be kept very low. This is also known as TSH suppression. You may be given thyroid hormone if only part of your thyroid gland
is removed.
TSH will be kept low for at least 1 year after radioactive iodine therapy or until you complete the surveillance testing.
Side-effects of thyroid hormone therapy treatment
- Too much thyroid hormone: Weight loss, feeling hot and sweaty, a fast heart rate, chest pain, cramps and diarrhoea. In the long term, it can cause weak bones (osteoporosis).
- Too little thyroid hormone: Weight gain, feeling cold, feeling tired, dry skin and dry hair.
If you have any side-effects, tell your doctor or nurse. Your doctor can do a blood test to make sure you are getting the right dose of thyroid hormone.
Coping with side-effects
The type of side-effects you get will depend on the type of treatment, the dose, the duration and your own general health.
Your doctor or nurse will discuss any possible side-effects with you before your treatment. We have more information about coping with the side effects of treatment.
Treating metastatic thyroid cancer
Metastatic or advanced thyroid cancer means the cancer has spread beyond the thyroid, to other parts of your body.
If you have metastatic thyroid cancer, your doctor will aim to slow down the growth of the cancer and reduce or relieve any symptoms you have.
Treatment includes chemotherapy, targeted therapies and radiotherapy. Or you may be suitable for a clinical trial.
Continue reading about thyroid cancer




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