Gall bladder cancer

Diagnosis and tests

Diagnosing gall bladder cancer

Your family doctor (GP) will talk to you about your symptoms. Your GP will do blood tests and refer you to hospital if they are concerned. Tests you might have include:

Your doctor will pass a thin, flexible tube through your mouth and into your stomach and bowel. Here they can look at your bile duct and check for any abnormal changes. They can also inject dye into the duct and check for blockages on an X-ray. They may also take a tissue sample (biopsy) which can be checked for cancer.

Read more about ERCP.

Your doctor passes a thin, flexible tube through your mouth and down into your stomach and bowel. A device called a probe is then put through the tube. This uses sound waves to look at organs near to your gall bladder.

Read more about EUS.

Your doctor puts a thin needle through your tummy and into your liver. A dye is injected into your bile duct so that your doctor can see any blockages on an X-ray.

Your doctor puts a thin needle through your tummy and into your liver. A dye is injected into your bile duct so that your doctor can see any blockages on an X-ray.

Your doctor will make a small cut in your tummy (abdomen) and put in a small, thin flexible tube with a camera attached to it. This lets your doctor look for any abnormal changes in your gall bladder and other organs, such as your liver. A sample of cells (biopsy) can be taken at this time. 

Read more about laparoscopy.

Your doctor makes a cut in your tummy (abdomen) to check for abnormal changes. A laparotomy can sometimes lead to more surgery, depending on what your doctor finds. For example, removing your gall bladder.

Read more about laparotomy.

A Daffodil Centre nurse smiles to camera wearing a navy uniform

If you are diagnosed with gall bladder cancer, we're here for you. 
Our cancer nurses are here if you need information or just want to talk. They can help you to understand your diagnosis and what to expect, send you information and tell you about our services. 

Further tests for gall bladder cancer

You may need further tests to give your doctors more information about your general health and about your cancer.  For example:

A type of X-ray to give a picture of the tissues inside your body. 

Read more about CT scans.

This is a scan that uses magnetic energy to build up a picture of the tissues inside your body. 

Read more about MRI scans.

A device like a microphone passed over your tummy to give a picture of your gall bladder and nearby organs. It can show any abnormal changes. 

Read more about ultrasound scans.

Blood tests can check how well your liver is working.

An X-ray that looks at the blood vessels around your gall bladder by injecting a special dye into them. This dye can be seen on the X-ray and shows if any blood vessels are blocked or affected by a tumour.  

The tests you have can help to:

  • Stage your cancer. This means finding out the size and position of the cancer.
  • Grade your cancer. This means looking at cancer cells under the microscope to learn about them and how they might grow.

Some tests may be used to see how you are responding to treatment. 

Waiting for test results

While some results may come back quickly, others may take a few weeks. Waiting for results can be an anxious time. It may help to talk things over with your doctor or nurse or with a relative or close friend. You can also call our Support Line on 1800 200 700 or visit a Daffodil Centre to speak to a cancer nurse.

What are the stages of gall bladder cancer?

Staging means finding out how big the cancer is and if it has spread to other parts of your body. Staging will help your doctor to plan the best treatment for you.

The staging system normally used in gall bladder cancer is called TNM. This stands for:

  • Tumour (T): How big is the tumour
  • Node (N): Has cancer spread your lymph nodes? How many nodes are affected?
  • Metastasis (M): Has the cancer has spread to other parts of your body?

Your doctor often uses this information to give your cancer a number stage – from 1 to 4.

A higher number means a more advanced cancer. Some stages are further divided into stage A and B. Your doctor will explain staging to you.

Knowing the stage of your cancer helps your team to plan the best treatment for you. 

The cancer is only affecting the wall of the gallbladder. It hasn't spread to other tissues or organs. 

The cancer has spread deeper into the layers of the wall of the gallbladder. It has not spread to other tissues or organs.

The cancer has spread to lymph nodes close to the gallbladder or has spread to nearby organs such as the liver, stomach, colon or small bowel.

The cancer has spread into two or more organs close to the gallbladder, or it has spread to distant lymph nodes or organs, such as the lungs. This is known as metastatic, advanced or secondary cancer.

Cross section of the gall bladder showing the different layers in the wall of the gall bladder

Grading gallbladder cancer

Grading describes how cancer cells look under a microscope compared with normal cells.  This will give your doctors an idea of how the cancer may grow and whether it is likely to spread. Knowing the grade helps doctors to plan your treatment.

Gallbladder cancer is graded from grade 1-3. Higher grades look more different to normal cells and tend to grow more quickly. 

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