2011 Research Publications

Irish Cancer Society-funded research produced the following 64 scientific publications in 2011:

All Cancers

Title: Inclusion of interactions in mathematical modelling of implant assisted magnetic drug targeting
Author(s): Cregg, PJ (Cregg, P. J.); Murphy, K (Murphy, Kieran); Mardinoglu, A (Mardinoglu, Adil)
Source: APPLIED MATHEMATICAL MODELLING  
Volume: 36  
Issue: 1  
Pages: 1-34  
DOI: 10.1016/j.apm.2011.05.036  
Published: JAN 2012  
ISSN: 0307-904X
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Title: Modifications to the Vilsmeier-Haack Formylation of 1,4-Dimethylcarbazole and Its Application to the Synthesis of Ellipticines
Author(s): Deane, FM (Deane, Fiona M.); Miller, CM (Miller, Charlotte M.); Maguire, AR (Maguire, Anita R.); McCarthy, FO (McCarthy, Florence O.)
Source: JOURNAL OF HETEROCYCLIC CHEMISTRY  
Volume: 48  
Issue: 4  
Pages: 814-823  
DOI: 10.1002/jhet.598  
Published: JUL 2011  
ISSN: 0022-152X
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Title: Regulation of the DNA Damage Response and Gene Expression by the Dot1L Histone Methyltransferase and the 53Bp1 Tumour Suppressor
Author(s): FitzGerald, J (FitzGerald, Jennifer); Moureau, S (Moureau, Sylvie); Drogaris, P (Drogaris, Paul); O'Connell, E (O'Connell, Enda); Abshiru, N (Abshiru, Nebiyu); Verreault, A (Verreault, Alain); Thibault, P (Thibault, Pierre); Grenon, M (Grenon, Muriel); Lowndes, NF (Lowndes, Noel F.)
Source: PLOS ONE  
Volume: 6  
Issue: 2  Article Number: e14714  
DOI: 10.1371/journal.pone.0014714  
Published: FEB 24 2011  
ISSN: 1932-6203
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Title: Pigment Epithelium-Derived Factor (PEDF) Interacts with Transportin SR2, and Active Nuclear Import Is Facilitated by a Novel Nuclear Localization Motif
Author(s): Anguissola, S (Anguissola, Sergio); McCormack, WJ (McCormack, William J.); Morrin, MA (Morrin, Michelle A.); Higgins, WJ (Higgins, Wayne J.); Fox, DM (Fox, Denise M.); Worrall, DM (Worrall, D. Margaret)
Source: PLOS ONE  
Volume: 6  
Issue: 10  Article Number: e26234  
DOI: 10.1371/journal.pone.0026234  
Published: OCT 18 2011  
ISSN: 1932-6203
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Title: Evaluation of the removal of point-of-sale tobacco displays in Ireland
Author(s): McNeill, A (McNeill, Ann); Lewis, S (Lewis, Sarah); Quinn, C (Quinn, Casey); Mulcahy, M (Mulcahy, Maurice); Clancy, L (Clancy, Luke); Hastings, G (Hastings, Gerard); Edwards, R (Edwards, Richard)
Source: TOBACCO CONTROL  
Volume: 20  
Issue: 2  
Pages: 137-143  
DOI: 10.1136/tc.2010.038141  
Published: MAR 2011  
ISSN: 0964-4563
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Title: Economic evaluation of the removal of tobacco promotional displays in Ireland
Author(s): Quinn, C (Quinn, Casey); Lewis, S (Lewis, Sarah); Edwards, R (Edwards, Richard); McNeill, A (McNeill, Ann)
Source: TOBACCO CONTROL  
Volume: 20  
ssue: 2  
Pages: 151-155  
DOI: 10.1136/tc.2010.039602  
Published: MAR 2011  
ISSN: 0964-4563
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Title: Methodological challenges in researching psychological distress and psychiatric morbidity among patients with advanced cancer: what does the literature (not) tell us?
Author(s): Ryan D, Gallagher P, Wright S, Cassidy E
Source: Palliat Med. 2011 May 11
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Myeloma

Title: PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells
Author(s): Maginn, EN (Maginn, E. N.); Browne, PV (Browne, P. V.); Hayden, P (Hayden, P.); Vandenberghe, E (Vandenberghe, E.); MacDonagh, B (MacDonagh, B.); Evans, P (Evans, P.); Goodyer, M (Goodyer, M.); Tewari, P (Tewari, P.); Campiani, G (Campiani, G.); Butini, S (Butini, S.); Williams, DC (Williams, D. C.); Zisterer, DM (Zisterer, D. M.); Lawler, MP (Lawler, M. P.); McElligott, AM (McElligott, A. M.)
Source: BRITISH JOURNAL OF CANCER  
Volume: 104  
Issue: 2  
Pages: 281-289  
DOI: 10.1038/sj.bjc.6606035  
Published: JAN 18 2011  
ISSN: 0007-0920
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Central Nervous System

Title: Imatinib and docetaxel in combination can effectively inhibit glioma invasion in an in vitro 3D invasion assay
Author(s): Kinsella, P (Kinsella, Paula); Clynes, M (Clynes, Martin); Amberger-Murphy, V (Amberger-Murphy, Verena)
Source: JOURNAL OF NEURO-ONCOLOGY  
Volume: 101
Issue: 2  
Pages: 189-198  
DOI: 10.1007/s11060-010-0246-1  
Published: JAN 2011  
ISSN: 0167-594X
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Hodgkin

Title: Bfl-1 is a crucial pro-survival nuclear factor-kappa B target gene in Hodgkin/Reed-Sternberg cells
Author(s): Loughran, ST (Loughran, Sinead T.); Campion, EM (Campion, Eva M.); D'Souza, BN (D'Souza, Brendan N.); Smith, SM (Smith, Sinead M.); Vrzalikova, K (Vrzalikova, Katerina); Wen, KS (Wen, Kaisheng); Murray, PG (Murray, Paul G.); Walls, D (Walls, Dermot)
Source: INTERNATIONAL JOURNAL OF CANCER  
Volume: 129  
Issue: 12  
Pages: 2787-2796  
DOI: 10.1002/ijc.25950  
Published: DEC 15 2011  
ISSN: 0020-7136
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Gastrointestinal Cancer

Title: COX-derived prostanoid pathways in Gastrointestinal Cancer development and progression: Novel targets for prevention and intervention
Author(s): Cathcart MC, O'Byrne KJ, Reynolds JV, O'Sullivan J, Pidgeon GP
Source: Biochim Biophys Acta. 2012 Jan;1825(1):49-63.
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Lung & Ovarian Cancer

Title: Erlotinib or gefitinib for the treatment of relapsed platinum pretreated non-small cell Lung Cancer and Ovarian Cancer: a systematic review
Author(s): Murphy M, Stordal B
Source: Drug Resist Updat. 2011 Jun;14(3):177-90.
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Ovarian Cancer

Title: Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in Ovarian Cancer cells
Author(s): Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J
Source: PLoS One. 2011;6(10):e26125. Epub 2011 Oct 12
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Title: 5-AZA-2 '-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer
Author(s): Saldova, R (Saldova, Radka); Dempsey, E (Dempsey, Eugene); Perez-Garay, M (Perez-Garay, Marta); Marino, K (Marino, Karina); Watson, JA (Watson, Jenny A.); Blanco-Fernandez, A (Blanco-Fernandez, Alfonso); Struwe, WB (Struwe, Weston B.); Harvey, DJ (Harvey, David J.); Madden, SF (Madden, Stephen F.); Peracaula, R (Peracaula, Rosa); McCann, A (McCann, Amanda); Rudd, PM (Rudd, Pauline M.)
Source: EPIGENETICS  
Volume: 6  
Issue: 11  
Pages: 1362-1372  
DOI: 10.4161/epi.6.11.17977  
Published: NOV 2011  
ISSN: 1559-2294
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Cervical Cancer

Title: Histology of cervical intraepithelial neoplasia and the role of biomarkers
Author(s): Martin, CM (Martin, Cara M.); O'Leary, JJ (O'Leary, John J.)
Source: BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY  
Volume: 25  
Issue: 5  
Pages: 605-615  
DOI: 10.1016/j.bpobgyn.2011.04.005  
Published: OCT 2011  
ISSN: 1521-6934
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Title: MYBL2 (B-MYB) in Cervical Cancer Putative Biomarker
Author(s): Astbury, K (Astbury, Katharine); McEvoy, L (McEvoy, Lynda); Brian, H (Brian, Hayes); Spillane, C (Spillane, Cathy); Sheils, O (Sheils, Orla); Martin, C (Martin, Cara); O'Leary, JJ (O'Leary, John J.)
Source: INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER  
Volume: 21  
Issue: 2  
Pages: 206-212  
DOI: 10.1097/IGC.0b013e318205759f  
Published: FEB 2011  
ISSN: 1048-891X
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Brain Tumour

Title: MicroRNA and DNA methylation alterations mediating retinoic acid induced neuroblastoma cell differentiation
Author(s): Stallings, RL (Stallings, Raymond L.); Foley, NH (Foley, Niamh H.); Bray, IM (Bray, Isabella M.); Das, S (Das, Sudipto); Buckley, PG (Buckley, Patrick G.)
Source: SEMINARS IN CANCER BIOLOGY  
Volume: 21  
Issue: 4  Pages: 283-290  
DOI: 10.1016/j.semcancer.2011.07.001  
Published: OCT 2011  
ISSN: 1044-579X
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Title: MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2
Author(s): Foley, NH (Foley, N. H.); Bray, I (Bray, I.); Watters, KM (Watters, K. M.); Das, S (Das, S.); Bryan, K (Bryan, K.); Bernas, T (Bernas, T.); Prehn, JHM (Prehn, J. H. M.); Stallings, RL (Stallings, R. L.)
Source: CELL DEATH AND DIFFERENTIATION  
Volume: 18  Issue: 7  
Pages: 1089-1098  
DOI: 10.1038/cdd.2010.172  
Published: JUL 2011  
ISSN: 1350-9047
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Title: Co-Localization of the Oncogenic Transcription Factor MYCN and the DNA Methyl Binding Protein MeCP2 at Genomic Sites in Neuroblastoma
Author(s): Murphy, DM (Murphy, Derek M.); Buckley, PG (Buckley, Patrick G.); Das, S (Das, Sudipto); Watters, KM (Watters, Karen M.); Bryan, K (Bryan, Kenneth); Stallings, RL (Stallings, Raymond L.)
Source: PLOS ONE  
Volume: 6  
Issue: 6
Article Number: e21436  
DOI: 10.1371/journal.pone.0021436  
Published: JUN 22 2011  
ISSN: 1932-6203
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Title: Dissection of the Oncogenic MYCN Transcriptional Network Reveals a Large Set of Clinically Relevant Cell Cycle Genes as Drivers of Neuroblastoma Tumorigenesis
Author(s): Murphy, DM (Murphy, Derek M.); Buckley, PG (Buckley, Patrick G.); Bryan, K (Bryan, Kenneth); Watters, KM (Watters, Karen M.); Koster, J (Koster, Jan); van Sluis, P (van Sluis, Peter); Molenaar, J (Molenaar, Jan); Versteeg, R (Versteeg, Rogier); Stallings, RL (Stallings, Raymond L.)
Source: MOLECULAR CARCINOGENESIS  
Volume: 50  
Issue: 6  
Pages: 403-411  
DOI: 10.1002/mc.20722  
Published: JUN 2011  
ISSN: 0899-1987
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Title: Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions
Author(s): Buckley, PG (Buckley, Patrick G.); Das, S (Das, Sudipto); Bryan, K (Bryan, Kenneth); Watters, KM (Watters, Karen M.); Alcock, L (Alcock, Leah); Koster, J (Koster, Jan); Versteeg, R (Versteeg, Rogier); Stallings, RL (Stallings, Raymond L.)
Source: INTERNATIONAL JOURNAL OF CANCER  
Volume: 128  
Issue: 10  
Pages: 2296-2305  
DOI: 10.1002/ijc.25584  
Published: MAY 1 2011  
ISSN: 0020-7136
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Title: Towards more specific O(6)-methylguanine-DNA methyltransferase (MGMT) inactivators
Author(s): Lopez, S (Lopez, Sergio); Margison, GP (Margison, Geoffrey P.); McElhinney, RS (McElhinney, R. Stanley); Cordeiro, A (Cordeiro, Alessandra); McMurry, TBH (McMurry, T. Brian H.); Rozas, I (Rozas, Isabel)
Source: BIOORGANIC & MEDICINAL CHEMISTRY  
Volume: 19  
Issue: 5  
Pages: 1658-1665  
DOI: 10.1016/j.bmc.2011.01.038  
Published: MAR 1 2011  
ISSN: 0968-0896
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Title: Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis
Author(s): Murphy DM, Buckley PG, Bryan K, Watters KM, Koster J, van Sluis P, Molenaar J, Versteeg R, Stallings RL
Source: Mol Carcinog. 2011 Jun;50(6):403-11.
DOI: 10.1002/mc.20722.
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Colorectal Cancer

Title: Integrated microfluidic array plate (iMAP) for cellular and molecular analysis
Author(s): Dimov, IK (Dimov, Ivan K.); Kijanka, G (Kijanka, Gregor); Park, Y (Park, Younggeun); Ducree, J (Ducree, Jens); Kang, T (Kang, Taewook); Lee, LP (Lee, Luke P.)
Source: LAB ON A CHIP  
Volume: 11  
Issue: 16  
Pages: 2701-2710  
DOI: 10.1039/c1lc20105k  
Published: 2011  
ISSN: 1473-0197
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Title: Fast-track protocols in Colorectal surgery
Author(s): Donohoe, CL (Donohoe, Claire L.); Mai, N (Mai Nguyen); Cook, J (Cook, Jessica); Murray, SG (Murray, Sarah Geagan); Chen, N (Chen, Nicole); Zaki, F (Zaki, Fardziana); Mehigan, BJ (Mehigan, Brian J.); McCormick, PH (McCormick, Paul H.); Reynolds, JV (Reynolds, John V.)
Source: SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND  
Volume: 9  
Issue: 2  
Pages: 95-103  
DOI: 10.1016/j.surge.2010.07.013  
Published: APR 2011  
ISSN: 1479-666X
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Prostate Cancer

Title: A RANDOMIZED TRIAL (IRISH CLINICAL ONCOLOGY RESEARCH GROUP 97-01) COMPARING SHORT VERSUS PROTRACTED NEOADJUVANT HORMONAL THERAPY BEFORE RADIOTHERAPY FOR LOCALIZED PROSTATE CANCER
Author(s): Armstrong, JG (Armstrong, John G.); Gillham, CM (Gillham, Charles M.); Dunne, MT (Dunne, Mary T.); Fitzpatrick, DA (Fitzpatrick, David A.); Finn, MA (Finn, Marie A.); Cannon, ME (Cannon, Mairin E.); Taylor, JC (Taylor, Judy C.); O'Shea, CM (O'Shea, Carmel M.); Buckney, SJ (Buckney, Steven J.); Thirion, PG (Thirion, Pierre G.)
Source: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS  
Volume: 81  
Issue: 1  
Pages: 35-45  
DOI: 10.1016/j.ijrobp.2010.04.065  
Published: SEP 1 2011  
ISSN: 0360-3016
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Title: Clinical potential of gene-directed enzyme prodrug therapy to improve radiation therapy in Prostate Cancer patients
Author(s): Vajda, A (Vajda, Alice); Marignol, L (Marignol, Laure); Foley, R (Foley, Ruth); Lynch, TH (Lynch, Thomas H.); Lawler, M (Lawler, Mark); Hollywood, D (Hollywood, Donal)
Source: CANCER TREATMENT REVIEWS
Volume: 37  
Issue: 8  
Pages: 643-654  
DOI: 10.1016/j.ctrv.2011.03.003  
Published: DEC 2011  
ISSN: 0305-7372
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Title: Ensemble based system for whole-slide Prostate Cancer probability mapping using color texture features
Author(s): DiFranco, MD (DiFranco, Matthew D.); O'Hurley, G (O'Hurley, Gillian); Kay, EW (Kay, Elaine W.); Watson, RWG (Watson, R. William G.); Cunningham, P (Cunningham, Padraig)
Source: COMPUTERIZED MEDICAL IMAGING AND GRAPHICS  
Volume: 35
Issue: 7-8  
Special Issue: SI  
Pages: 629-645  
DOI: 10.1016/j.compmedimag.2010.12.005  
Published: OCT-DEC 2011  
ISSN: 0895-6111
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Title: Epstein criteria for insignificant Prostate Cancer
Author(s): Oon, SF (Oon, Sheng F.); Watson, RW (Watson, R. William); O'Leary, JJ (O'Leary, John J.); Fitzpatrick, JM (Fitzpatrick, John M.)
Source: BJU INTERNATIONAL  
Volume: 108  
Issue: 4  
Pages: 518-525  
DOI: 10.1111/j.1464-410X.2011.09979.x  
Published: AUG 2011  
ISSN: 1464-4096
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Title: A METHOD FOR THE PREDICTION OF LATE ORGAN-AT-RISK TOXICITY AFTER RADIOTHERAPY OF THE PROSTATE USING EQUIVALENT UNIFORM DOSE
Author(s): Fleming, C (Fleming, Cathy); Kelly, C (Kelly, Colin); Thirion, P (Thirion, Pierre); Fitzpatrick, K (Fitzpatrick, Kathryn); Armstrong, J (Armstrong, John)
Source: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS  
Volume: 80  
Issue: 2
 Pages: 608-613  
DOI: 10.1016/j.ijrobp.2010.07.1994  
Published: JUN 1 2011  
ISSN: 0360-3016
________________________________________
Title: Androgen Hypersensitivity in Prostate Cancer: Molecular Perspectives on Androgen Deprivation Therapy Strategies
Author(s): Foley, R (Foley, Ruth); Marignol, L (Marignol, Laure); Keane, JP (Keane, John P.); Lynch, TH (Lynch, Thomas H.); Hollywood, D (Hollywood, Donal)
Source: PROSTATE  
Volume: 71  
Issue: 5  
Pages: 550-557  
DOI: 10.1002/pros.21266  
Published: APR 2011  
ISSN: 0270-4137
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Title: Biomarker research in Prostate Cancer-towards utility, not futility
Author(s): Oon, SF (Oon, Sheng Fei); Pennington, SR (Pennington, Stephen R.); Fitzpatrick, JM (Fitzpatrick, John M.); Watson, RWG (Watson, R. William G.)
Source: NATURE REVIEWS UROLOGY  
Volume: 8  
Issue: 3  
Pages: 131-138  
DOI: 10.1038/nrurol.2011.11  
Published: MAR 2011  
ISSN: 1759-4812
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Title: Applying Random Forests To Identify Biomarker Panels in Serum 2D-DIGE Data for the Detection and Staging of Prostate Cancer
Author(s): Fan, Y (Fan, Yue); Murphy, TB (Murphy, Thomas Brendan); Byrne, JC (Byrne, Jennifer C.); Brennan, L (Brennan, Lorraine); Fitzpatrick, JM (Fitzpatrick, John M.); Watson, RWG (Watson, R. William G.)
Source: JOURNAL OF PROTEOME RESEARCH  
Volume: 10  
Issue: 3  
Pages: 1361-1373  
DOI: 10.1021/pr1011069  
Published: MAR 2011  
ISSN: 1535-3893
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Title: Core fucosylation and alpha 2-3 sialylation in serum N-glycome is significantly increased in Prostate Cancer comparing to benign prostate hyperplasia
Author(s): Saldova, R (Saldova, Radka); Fan, Y (Fan, Yue); Fitzpatrick, JM (Fitzpatrick, John M.); Watson, RWG (Watson, R. William G.); Rudd, PM (Rudd, Pauline M.)
Source: GLYCOBIOLOGY  
Volume: 21  
Issue: 2  
Pages: 195-205  
DOI: 10.1093/glycob/cwq147  
Published: FEB 2011  
ISSN: 0959-6658
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Title: In Silico Analysis and DHPLC Screening Strategy Identifies Novel Apoptotic Gene Targets of Aberrant Promoter Hypermethylation in Prostate Cancer
Author(s): Murphy, TM (Murphy, Therese M.); Sullivan, L (Sullivan, Linda); Lane, C (Lane, Caroline); O'Connor, L (O'Connor, Lisa); Barrett, C (Barrett, Ciara); Hollywood, D (Hollywood, Donal); Lynch, T (Lynch, Thomas); Lawler, M (Lawler, Mark); Perry, AS (Perry, Antoinette S.)
Source: PROSTATE  
Volume: 71
Issue: 1  
Pages: 1-17  
DOI: 10.1002/pros.21212  
Published: JAN 1 2011  
ISSN: 0270-4137
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Title: Androgen hypersensitivity in Prostate Cancer: molecular perspectives on androgen deprivation therapy strategies
Author(s): Foley R, Marignol L, Keane JP, Lynch TH, Hollywood D
Source: Prostate. 2011 Apr;71(5):550-7.
DOI: 10.1002/pros.21266
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Title: Androgen hypersensitivity in Prostate Cancer: molecular perspectives on androgen deprivation therapy strategies
Author(s): Foley R, Marignol L, Keane JP, Lynch TH, Hollywood D
Source: Prostate. 2011 Apr;71(5):550-7.
DOI: 10.1002/pros.21266.
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Breast & Prostate Cancer

Title: Social welfare and legal constraints associated with work among Breast and Prostate Cancer survivors: experiences from Ireland
Author(s): Sharp, L (Sharp, Linda); Timmons, A (Timmons, Aileen)
Source: JOURNAL OF CANCER SURVIVORSHIP-RESEARCH AND PRACTICE  
Volume: 5  
Issue: 4  
Pages: 382-394  
DOI: 10.1007/s11764-011-0183-9  
Published: DEC 2011  
ISSN: 1932-2259
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Title: Social welfare and legal constraints associated with work among Breast and Prostate Cancer survivors: experiences from Ireland
Author(s): Sharp L, Timmons A
Source: J Cancer Surviv. 2011 Dec;5(4):382-94.
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Breast Cancer

Title: Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter Supports Radionuclide Imaging and Treatment of Breast Cancer
Author(s): Dwyer, RM (Dwyer, Roisin M.); Ryan, J (Ryan, James); Havelin, RJ (Havelin, Ronan J.); Morris, JC (Morris, John C.); Miller, BW (Miller, Brian W.); Liu, ZL (Liu, Zhonglin); Flavin, R (Flavin, Richard); O'Flatharta, C (O'Flatharta, Cathal); Foley, MJ (Foley, Mark J.); Barrett, HH (Barrett, Harrison H.); Murphy, JM (Murphy, J. Mary); Barry, FP (Barry, Frank P.); O'Brien, T (O'Brien, Timothy); Kerin, MJ (Kerin, Michael J.)
Source: STEM CELLS  
Volume: 29
Issue: 7  
Pages: 1149-1157  
DOI: 10.1002/stem.665  
Published: JUL 2011  
ISSN: 1066-5099
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Title: The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue
Author(s): Ryan, J (Ryan, James); Curran, CE (Curran, Catherine E.); Hennessy, E (Hennessy, Emer); Newell, J (Newell, John); Morris, JC (Morris, John C.); Kerin, MJ (Kerin, Michael J.); Dwyer, RM (Dwyer, Roisin M.)
Source: PLOS ONE  
Volume: 6  
Issue: 1  
Article Number: e16023  
DOI: 10.1371/journal.pone.0016023  
Published: JAN 19 2011  
ISSN: 1932-6203
________________________________________
Title: RACK1, A multifaceted scaffolding protein: Structure and function
Author(s): Adams, DR (Adams, David R.); Ron, D (Ron, Dorit); Kiely, PA (Kiely, Patrick A.)
Source: CELL COMMUNICATION AND SIGNALING  
Volume: 9  
Article Number: 22  
DOI: 10.1186/1478-811X-9-22  
Published: OCT 6 2011  
ISSN: 1478-811X
________________________________________
Title: Targeting of Breast Metastases Using a Viral Gene Vector with Tumour-selective Transcription
Author(s): Rajendran, S (Rajendran, Simon); Collins, S (Collins, Sara); Van Pijkeren, JP (Van Pijkeren, Jan P.); O'Hanlon, D (O'Hanlon, Deirdre); O'Sullivan, GC (O'Sullivan, Gerald C.); Tangney, M (Tangney, Mark)
Source: ANTICANCER RESEARCH  
Volume: 31  
Issue: 5  
Pages: 1627-1635  
Published: MAY 2011  
ISSN: 0250-7005
________________________________________
Title: Preclinical evaluation of gene delivery methods for the treatment of loco-regional disease in Breast Cancer
Author(s): Rajendran, S (Rajendran, Simon); O'Hanlon, D (O'Hanlon, Deirdre); Morrissey, D (Morrissey, David); O'Donovan, T (O'Donovan, Tracey); O'Sullivan, GC (O'Sullivan, Gerald C.); Tangney, M (Tangney, Mark)
Source: EXPERIMENTAL BIOLOGY AND MEDICINE  
Volume: 236  
Issue: 4  
Pages: 423-434  
DOI: 10.1258/ebm.2011.010234  
Published: APR 2011  
ISSN: 1535-3702
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Leukemia

Title: Autophagy induction by Bcr-Abl-expressing cells facilitates their recovery from a targeted or nontargeted treatment
Author(s):
Crowley LC, Elzinga BM, O'Sullivan GC, McKenna SL.
Source: Am J Hematol. 2011 Jan;86(1):38-47
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Title: Microtubule-targeting-compound PBOX-15 radiosensitizes cancer cells in vitro
Author(s): Forde, JC (Forde, James C.); Maginn, EN (Maginn, Elaina N.); McNamara, G (McNamara, Gillian); Martin, LM (Martin, Lynn M.); Campiani, G (Campiani, Guiseppe); Williams, DC (Williams, D. Clive); Zisterer, D (Zisterer, Daniela); McElligott, AM (McElligott, Anthony M.); Lawler, M (Lawler, Mark); Lynch, TH (Lynch, Thomas H.); Hollywood, D (Hollywood, Donal); Marignol, L (Marignol, Laure)
Source: CANCER BIOLOGY & THERAPY  
Volume: 11  
Issue: 4  
Pages: 421-428  
DOI: 10.4161/cbt.11.4.14183  
Published: FEB 15 2011  
ISSN: 1538-4047
________________________________________
Title: Autophagy induction by Bcr-Abl-expressing cells facilitates their recovery from a targeted or nontargeted treatment
Author(s): Crowley, LC (Crowley, Lisa C.); Elzinga, BM (Elzinga, Baukje M.); O'Sullivan, GC (O'Sullivan, Gerald C.); McKenna, SL (McKenna, Sharon L.)
Source: AMERICAN JOURNAL OF HEMATOLOGY  
Volume: 86
Issue: 1  
Pages: 38-47  
DOI: 10.1002/ajh.21914  
Published: JAN 2011  
ISSN: 0361-8609
________________________________________
Title: Hydrogen peroxide: a Jekyll and Hyde signalling molecule
Author(s): Gough, DR (Gough, D. R.); Cotter, TG (Cotter, T. G.)
Source: CELL DEATH & DISEASE  
Volume: 2  
Article Number: e213  
DOI: 10.1038/cddis.2011.96  
Published: OCT 2011  
ISSN: 2041-4889
________________________________________
Title: Inhibition of Protein-tyrosine Phosphatase 1B (PTP1B) Mediates Ubiquitination and Degradation of Bcr-Abl Protein
Author(s): Alvira, D (Alvira, Daniel); Naughton, R (Naughton, Ruth); Bhatt, L (Bhatt, Lavinia); Tedesco, S (Tedesco, Sara); Landry, WD (Landry, William D.); Cotter, TG (Cotter, Thomas G.)
Source: JOURNAL OF BIOLOGICAL CHEMISTRY  
Volume: 286  
Issue: 37  
Pages: 32313-32323  
DOI: 10.1074/jbc.M111.249060  
Published: SEP 16 2011  
ISSN: 0021-9258
________________________________________

Lung Cancer

Title: Prostacyclin Synthase Expression and Epigenetic Regulation in Nonsmall Cell Lung Cancer
Author(s): Cathcart, MC (Cathcart, Mary-Clare); Gray, SG (Gray, Steven G.); Baird, AM (Baird, Anne-Marie); Boyle, E (Boyle, Elaine); Gately, K (Gately, Kathy); Kay, E (Kay, Elaine); Cummins, R (Cummins, Robert); Pidgeon, GP (Pidgeon, Graham P.); O'Byrne, KJ (O'Byrne, Kenneth J.)
Source: CANCER
Volume: 117
ssue: 22  Pages: 5121-5132  
DOI: 10.1002/cncr.26168  
Published: NOV 15 2011  
ISSN: 0008-543X
________________________________________
Title: Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell Lung Cancer
Author(s): Cathcart, MC (Cathcart, Mary-Clare); Gately, K (Gately, Kathy); Cummins, R (Cummins, Robert); Kay, E (Kay, Elaine); O'Byrne, KJ (O'Byrne, Kenneth J.); Pidgeon, GP (Pidgeon, Graham P.)
Source: MOLECULAR CANCER  
Volume: 10  
Article Number: 25  
DOI: 10.1186/1476-4598-10-25  
Published: MAR 9 2011  
ISSN: 1476-4598
________________________________________

Oesophageal Cancer

Title: The impact of young age on outcomes in Esophageal and Junctional Cancer
Author(s): Donohoe, CL (Donohoe, C. L.); MacGillycuddy, E (MacGillycuddy, E.); Reynolds, JV (Reynolds, J. V.)
Source: DISEASES OF THE ESOPHAGUS
Volume: 24
Issue: 8
Pages: 560-568  
DOI: 10.1111/j.1442-2050.2011.01183.x  
Published: NOV 2011  
ISSN: 1120-8694
________________________________________
Title: Perioperative evaluation of the obese patient
Author(s): Donohoe, CL (Donohoe, Claire L.); Feeney, C (Feeney, Ciara); Carey, MF (Carey, Michael F.); Reynolds, JV (Reynolds, John V.)
Source: JOURNAL OF CLINICAL ANESTHESIA
Volume: 23  
Issue: 7  
Pages: 575-586  
DOI: 10.1016/j.jclinane.2011.06.005  
Published: NOV 2011  
ISSN: 0952-8180
________________________________________
Title: Serum Proteomic Profiling Reveals That Pretreatment Complement Protein Levels are Predictive of Esophageal Cancer Patient Response to Neoadjuvant Chemoradiation
Author(s): Maher, SG (Maher, Stephen G.); McDowell, DT (McDowell, Dermot T.); Collins, BC (Collins, Ben C.); Muldoon, C (Muldoon, Cian); Gallagher, WM (Gallagher, William M.); Reynolds, JV (Reynolds, John V.)
Source: ANNALS OF SURGERY  
Volume: 254  
Issue: 5  
Pages: 809-817  
DOI: 10.1097/SLA.0b013e31823699f2  
Published: NOV 2011  
ISSN: 0003-4932
________________________________________
Title: Long-Term Health-Related Quality of Life for Disease-Free Esophageal Cancer Patients
Author(s): Donohoe, CL (Donohoe, Claire L.); McGillycuddy, E (McGillycuddy, Erin); Reynolds, JV (Reynolds, John V.)
Source: WORLD JOURNAL OF SURGERY  
Volume: 35  
Issue: 8
Pages: 1853-1860  
DOI: 10.1007/s00268-011-1123-6  
Published: AUG 2011  
ISSN: 0364-2313
________________________________________
Title: Visceral adiposity, insulin resistance and cancer risk
Author(s): Donohoe, CL (Donohoe, Claire L.); Doyle, SL (Doyle, Suzanne L.); Reynolds, JV (Reynolds, John V.)
Source: DIABETOLOGY & METABOLIC SYNDROME  
Volume: 3  
Article Number: 12  
DOI: 10.1186/1758-5996-3-12  
Published: JUN 22 2011  
ISSN: 1758-5996
________________________________________
Title: Cancer Cachexia: Mechanisms and Clinical Implications
Author(s): Donohoe, CL (Donohoe, Claire L.); Ryan, AM (Ryan, Aoife M.); Reynolds, JV (Reynolds, John V.)
Source: GASTROENTEROLOGY RESEARCH AND PRACTICE  
Article Number: 601434  
DOI: 10.1155/2011/601434  
Published: 2011  
ISSN: 1687-6121
________________________________________
Title: Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
Author(s): Lysaght J, van der Stok EP, Allott EH, Casey R, Donohoe CL, Howard JM, McGarrigle SA, Ravi N, Reynolds JV, Pidgeon GP
Source: Cancer Lett. 2011 Dec 15;312(1):62-72.
________________________________________
Title: T lymphocyte activation in visceral adipose tissue of patients with Oesophageal adenocarcinoma
Author(s): Lysaght J, Allott EH, Donohoe CL, Howard JM, Pidgeon GP, Reynolds JV
Source: Br J Surg. 2011 Jul;98(7):964-74.
DOI: 10.1002/bjs.7498.
________________________________________
Title: Basic concepts of inflammation and its role in carcinogenesis
Author(s): Maher SG, Reynolds JV
Source: Recent Results Cancer Res. 2011;185:1-34
________________________________________
Title: Evidence-based selective application of transhiatal esophagectomy in a high-volume Esophageal center.
Author(s): Donohoe CL, O'Farrell NJ, Ravi N, Reynolds JV
Source: World J Surg. 2012 Jan;36(1):98-103
________________________________________
Title: Modern oncologic and operative outcomes for Oesophageal Cancer treated with curative intent
Author(s): Reynolds JV, McGillycuddy E, Ravi N, Donohoe C, O'Toole D, O'Byrne K, Hollywood D
Source: Ir Med J. 2011 Sep;104(8):235-8
________________________________________
Title: IGF-1 and Its Receptor in Esophageal Cancer: Association with Adenocarcinoma and Visceral Obesity
Author(s): Doyle SL, Donohoe CL, Finn SP, Howard JM, Lithander FE, Reynolds JV, Pidgeon GP, Lysaght J
Source: Am J Gastroenterol. 2011 Dec 6.
DOI: 10.1038/ajg.2011.417.
________________________________________
Title: MMP9 expression in Oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation
Author(s): Allott EH, Lysaght J, Cathcart MC, Donohoe CL, Cummins R, McGarrigle SA, Kay E, Reynolds JV, Pidgeon GP
Source: Mol Carcinog. 2011 Nov 28.
DOI: 10.1002/mc.21840
________________________________________
Title: Visceral adiposity, insulin resistance and cancer risk.
Author(s): Donohoe CL, Doyle SL, Reynolds JV
Source: Diabetol Metab Syndr. 2011 Jun 22;3:12
________________________________________