Treatments for locally advanced prostate cancer

Locally advanced prostate cancer

If your prostate cancer has spread outside of the prostate gland into nearby tissues it is called locally advanced prostate cancer.  This may include spread to your lymph nodes, bladder back passage (rectum) or your seminal vesicles. The 2 seminal vesicles are glands which produce some of the fluid in semen and sit just behind the prostate gland.

What are the treatments for locally advanced prostate cancer?

Locally advanced prostate cancer can be treated in a number of ways. The best treatment for you will depend on a number of different things so it isn’t possible to say which treatment is best overall.

Sometimes treatment for locally advanced prostate cancer aims to get rid of prostate cancer completely. If it is not possible to get rid of the cancer the treatment aims to control it and to stop it growing.

Your doctor will decide which treatment or combination of treatments is suitable for you. This will be decided with you once you have your test results.
Your doctor will consider factors such as:
  • The stage of your cancer - whether it has spread just outside the prostate gland, how far outside, or whether it may have spread to other parts of your body.
  • The grade of your cancer ( how fast the cancer cells are dividing and their appearance under the microscope)
  • Your PSA level
  • If you have urinary symptoms or not
  • Your general health

Types of treatment for locally advanced prostate cancer

The main treatments for prostate cancer that has spread outside your prostate gland are. 

Deciding on treatment for locally advanced prostate cancer

Sometimes men with prostate cancer are asked to decide between treatment choices. If this happens to you before you make your decision you should make sure you know:
  • What the treatment involves
  • The possible side-effects
  • The advantages and disadvantages
  • How your treatment will be monitored

Asking questions

At this time you may be anxious about what is going to happen next. You can ask your doctor and nurse as many questions as you like, no matter how small or trivial you think they are. All questions are important. Write down your questions as you think of them and bring them with you to your hospital visits.

Can I seek other medical opinions?

You might find it reassuring to have another medical opinion to help you decide about your treatment. Do not worry that you are offending your doctor by doing this. He or she will gladly refer you to another specialist for their opinion if you feel that this would be helpful.
You have the right to find out what a treatment option means for you, and the right to accept or refuse it. If you want to refuse treatment, let your doctor or nurse know your concerns first. It may help to talk to your GP as well. The important thing is that you are fully aware of the benefits and risks.

Prostate Cancer Patients’ Charter

The Prostate Cancer Patients’ Charter outlines the standard of services that men with prostate cancer in Ireland should be entitled to from the time of diagnosis and treatment, through to learning to live with the potential effects of the illness or its treatment.
For more information on the Prostate Cancer Patients’ Charter please see our information leaflet Prostate Cancer Patients’ Charter.

Further support

Talking to another man who has been in a similar situation can be helpful when you are deciding on treatment.  Call our Cancer Nurseline on 1800 200 700 and we can put you in contact with a trained volunteer who has dealt with a  prostate  cancer diagnosis themselves and knows what you are going through.
You could also join our online community and post questions or messages anonymously to other male members undergoing or who have finished treatment for prostate cancer. Visit our online community.
If you forget to ask a question while you are with the doctor or would like more information or need explanations, call our Cancer Nurseline on 1800 200 700 or visit a Daffodil Centre to talk to a cancer nurse in confidence. You can also email the nurses at  Click here to find your nearest Daffodil Centre.
Date Last Reviewed: 
Wednesday, July 16, 2014
Date Last Revised: 
Wednesday, April 15, 2015