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Carboplatin is a chemotherapy drug that is used to treat some types of cancer including ovarian and lung cancer. It is usually used in combination with other chemotherapy drugs. It may be helpful to read the general chemotherapy information section together with this section, as it will give more advice on chemotherapy side effects.
It is a colourless fluid.
It is given as an injection or infusion intravenously into a peripheral cannula or into a central line.
The side effects mentioned below may not affect every one, as each patient’s reaction to chemotherapy is different. It will also depend on how many chemotherapy drugs you are receiving. If you experience any effects that you think is related to your chemotherapy, please discuss them with your oncology doctor or chemotherapy nurse.
You will be more prone to infection as Carboplatin affects your white cell production from the bone marrow. This effect usually occurs about 7 days after your chemotherapy. Your white cells, however, do gradually recover and are usually within normal ranges for your next chemotherapy course.
You should contact your doctor or the Oncology Unit straight away if you if you have a sore throat,cough, pain passing urine, redness and swelling at e.g. at a catheter site. Or have a temperature of 38 degrees° C or greater.
You may feel lethargic and breathless due to a reduction in your red cells, caused by Carboplatin. Inform your doctor if you are feeling these effects.
Carboplatin can also affect the production of platelets, which can cause bleeding or bruising. Inform your doctor if you notice any unexplained bleeding or bruising.
You may feel very tired. This can last for a few months after your treatment. Inform your doctor or nurse of how you are feeling.
You may find that your appetite decreases while receiving chemotherapy. You should maintain a healthy diet and ask to speak to your dietician if you have any worries.
Carboplatin can make you feel sick nausea or to to be sick vomit . When this occurs can vary. Your doctor will prescribe some medications to prevent this anti-emetics . If you continue to feel sick it is important to inform your doctor.
This is extremely rare with this drug but you may loose all your hair or it may just thin out. This usually happens after your first course of chemotherapy. This is temporary and your hair will grow back.
You may develop a sore mouth or ulcers due to your chemotherapy. You will be prescribed some mouthwashes. Inform your doctor or nurse if your mouth becomes sore or you develop ulcers. You may also experience some taste changes, which will resolve after you finish your treatment.
It is important to tell your doctor if you are experiencing this symptom. It can be treated with medications.
Carboplatin can cause some changes to your kidney function. You will have regular blood teats taken before your treatment to assess this.
You may experience some hearing loss or ringing in your ears but this is rare. You should inform your doctor if you have any hearing changes.
This is caused by the effect of Carboplatin on the nerves and can also be called peripheral neuropathy. You may also experience pain and find it difficult to do up buttons.
It is an unusual symptom unless you receive high doses of the drug. It usually disappears after the treatment has stopped. You should inform your doctor if you are experiencing this symptom, as there are medications that can be given to relieve it.
This reaction can occur while the chemotherapy drug is infusing. You may develop facial flushing, shortness of breath or a rash. This is rare and usually occurs in people who have received the drug previously.
It is important to discuss this with your doctor as Carboplatin may affect your fertility.
It is important to use a reliable form of contraception while you are on treatment and for at least two years after your treatment has completed. It is not advised to get pregnant while on treatment as the drugs may affect the foetus.
It is important to inform your doctor of any medications that you are taking, including over the counter medications or herbal drugs as they can interfere with some chemotherapy drugs.
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